|
(Anne Fay)
Prick skin tests:
1. Are more sensitive than intradermal tests. False
2. Are read at 48 hours. False
3. Are a convenient method for detecting allergic reactions
in most patients True.
4. Cannot be used for food allergens False.
5. Can be performed using a 25 gauge needle True.
Drugs which interfere with prick tests include:
6. Azelastine eye drops. False
7. Oral steroids True.
8. Ceterizine. True
9. Tricyclic antidepressants. True
10. Cromoglycate. True
(CC Bunn & VJ Tormey)
Anti-centromere antibodies
11. Are readily detectable using saline soluble antigen
extracts. False
12. Are highly specific for DcSSc. False
13. CENP-B antibodies are detected in all patients with
ACA. True
14. Usually occur in young SSc patients. False
15. Are usually present in high titre. True
The following autoantibodies are associated with internal
organ involvement in SSc.
16. ATA and pulmonary fibrosis. True
17. AFA and primary pulmonary hypertension. True
18. RNA polymerase and myositis. False
19. PmScl and renal involvement. False
20. ThRNP and pulmonary hypertension. True
The following statements are true
21. Radioimmunoprecipitation methods are useful in the detection
of RNA polymerase. True
22. CIE and double diffusion are more sensitive than radioimmuno-precipitation.
False
23. Anti-aminoacyl tRNA synthetases are never found in SSc.
False
24. ATA and ARA are mutually exclusive in SSc. True
25. AFA are more common in Caucasians. False
(Ian Hutchinson & Ali Hajeer)
A polymorphism can be
26. a minisatellite True
27. a microsatellite True
28. a SNP True
29. in any part of the gene True
30. found only in cytokines False
SNPs
31. can be identified by SSCP & heteroduplex analysis
True
32. within coding regions are called cSNPs True
33. cSNP can not cause amino acid change False
34. occur on average every 10Kb False
35. occur only within promoters and can alter transcription
factors binding False
(Karim MY, Khamashta MA & Hughes GRV)
Regarding the antiphospholipid syndrome (Hughes' syndrome)
36. Anticoagulation with heparin is the treatment of choice
False
37. Preliminary diagnostic criteria now exist True
38. Venous but not arterial thromboses are characteristic
False
39. Immunosuppression is the mainstay of treatment False
40. Initial thrombosis can occur with the use of oestrogen-containing
oral contraceptives True
Regarding the investigation of the antiphospholipid
syndrome (Hughes' syndrome)
41. IgA anticardiolipin antibodies should be ordered routinely
False
42. Requesting lupus anticoagulant is not required if anticardiolipin
antibodies are requested False
43. Thrombocytopenia is not usually severe True
44. Anticardiolipin antibodies are frequently measured by
ELISA True
45. Anticardiolipin antibody titre is strongly correlated
with severity of clinical features False
(Lawrence Youlten)
Anaphylactic reactions to intravenous anaesthetic drugs
46. Are more common in women than in men True
47. Depend on previous drug exposure False
48. Occur only in atopic individuals False
49. Are usually apparent within three minutes True
50. Are never IgE mediated False
Skin-prick tests with drugs used in anaesthesia
51. Are more hazardous than intradermal tests False
52. Are more useful than blood tests in identifying responsible
drugs True
53. May produce false positive results True
54. Should only be carried out with very dilute drug solutions
False
55. Should be read at 10 to 15 minutes True
(S. Katona, C.McGavin & E.Kaminski)
Seminal plasma protein allergy:
56. Is not usually associated with atopy. False
57. May be confused with latex allergy. True
58. Usually causes a local vaginitis without systemic symtoms.
False
59. Is a type IV hypersensitivity reaction. False
60. Reactions do not occur with a patients first sexual
intercourse. False
61. Symptoms may be intermittent. True
62. Specific IgE to seminal plasma proteins is a sensitive
test for SPPA. False
|